Prolific science writer Michael Gross, author of Light and Life and numerous other books and articles (and a regular contributor to Chemistry World), wrote a terrific article in the Guardian back in 2003 called "Eat my Lab Coat" about the value of watching the Simpsons for its science. Here's a link:
Eat My Lab Coat by Michael Gross.
He maintains an intriguing blog that spans topics ranging from biochemistry and politics to Shakira. Check it out: