There's a great new article in the Chronicle of Higher Education that shows how The Simpsons could be used to study religion, science, literature and psychology.
A quote from the article:
"Paul Halpern, author of What's Science Ever Done for Us: What the Simpsons Can Teach Us About Physics, Robots, Life, and the Universe (Wiley, 2007) and a physics professor at the University of the Sciences in Philadelphia, says even though the show is not always completely correct, it introduces [scientific] concepts."
A link to the full article:
The Cerebral Simpsons